Relationship between the Korean Version Survey of the Autonomic Symptoms Score and Cardiac Autonomic Neuropathy Parameters in Patients with Diabetic Peripheral Neuropathy.
10.4093/dmj.2014.38.5.349
- Author:
Sun Hee KIM
1
;
Kyung Ae LEE
;
Heung Yong JIN
;
Hong Sun BAEK
;
Tae Sun PARK
Author Information
1. Division of Endocrinology and Metabolism, Department of Internal Medicine, Research Institute of Clinical Medicine, Chonbuk National University Hospital, Chonbuk National University Medical School, Jeonju, Korea. pts@jbnu.ac.kr
- Publication Type:Original Article
- Keywords:
Autonomic neuropathy;
Diabetes;
Survey of autonomic symptom scale
- MeSH:
Diabetic Neuropathies;
Humans;
Hypotension, Orthostatic;
Jeollabuk-do;
Korea;
Mass Screening;
Peripheral Nervous System Diseases*
- From:Diabetes & Metabolism Journal
2014;38(5):349-355
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: The Survey of Autonomic Symptom (SAS) scale was reported as an easy instrument to assess the autonomic symptoms in patients with early diabetic neuropathy. In this study, we investigated the relationship between the SAS scale and the parameters of cardiac autonomic neuropathy (CAN) in Korean patients with diabetic peripheral neuropathy (DPN). METHODS: The SAS scale was tested in 30 healthy controls and 73 patients with DPN at Chonbuk National University Hospital, in Korea. The SAS score was compared to the parameters of the CAN test and the total symptom score (TSS) for DPN in patients with DPN. RESULTS: The SAS symptom score and total impact score were increased in patients with DPN compared to the control group (P=0.01), particularly in sudomotor dysfunction (P=0.01), and vasomotor dysfunction (P=0.01). The SAS score was increased in patients with CAN compared to patients without CAN (P<0.05). Among the diverse CAN parameters, the valsalva ratio and postural hypotension were associated with the SAS score (P<0.05). However, there was no association between the SAS scale and TSS for DPN, and TSS for DPN did not differ between patients with and without CAN. CONCLUSION: SAS is a simple instrument that can be used to assess autonomic symptoms in patients with diabetes and can be used as a screening tool for autonomic neuropathy, particularly for CAN.
