Synthesis and surface modification of magnetic silica micro-spheres and Its application in biomedicine
10.3760/cma.j.issn.1673-4181.2010.02.015
- VernacularTitle:磁性SiO2微球的制备、表面修饰及其在生物医学领域的应用
- Author:
Tao HAN
;
Qingping XIAO
;
Zhongrong SONG
- Publication Type:Journal Article
- Keywords:
Magnetic;
Silica;
Synthesis;
Surface modification;
Application
- From:
International Journal of Biomedical Engineering
2010;33(2):125-封3
- CountryChina
- Language:Chinese
-
Abstract:
Magnetic silica micro-spheres is a kind of novel functional materials, which is expected to be applied to targeted drug delivery, immunomagnetic beads, separation of nucleic acid and protein, immobilization of enzymes and isolation and purification of natural products in biomedicine. This review describes the methods of synthesis, surface modification and applications of magnetic silica micro-spheres, which focus on the various strategies in synthesis with core-shell and mosaic structure, sol-gel method, liquid phase deposition, self-assembly technique and micro-emulsion method. Finally, foregroud and prospect of the research are also discussed.
