Progress in research on the role of heme oxygenase-1 in cardiovascular diseases
- VernacularTitle:血红素加氧酶-1在心血管疾病中的作用研究新进展
- Author:
Tingting LI
;
Yuan GUO
- Publication Type:Journal Article
- Keywords:
heme oxygenase-1;
carbon monoxide;
bilirubin;
hypertension;
atherosclerosis
- From:
Basic & Clinical Medicine
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Heme oxygenase-1(HO-1) is an inducible stress protein.In addition to its role in heme degradation,several positive biological effects exerted by this enzyme have highlighted in recent years as anti-inflammatory,anti-apoptotic,anti-proliferative and cytoprotective functions.This oxidase system with multiple functions takes part in the pathophysiology of cardiovascular system.It is related to a variety of cardiovascular diseases including hypertension,atherosclerosis,ischemia/reperfusion injury and postangioplasty restenosis.
