Diagnosis and treatment of renal oncocytoma and chromophobe cell renal carcinoma
- VernacularTitle:肾嗜酸细胞瘤和嫌色细胞癌的临床鉴别诊断及治疗
- Author:
Haidong WANG
;
Ping ZHANG
;
Libo MAN
;
Yuhai ZHANG
- Publication Type:Journal Article
- Keywords:
renal oncocytoma;
chromophobe cell renal carcinoma;
diagnosis;
treatment
- From:
Basic & Clinical Medicine
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical characteristic,diagnosis and treatment procedures for renal oncocytoma and chromophobe cell renal carcinoma.Methods Eight cases of renal oncocytoma and 5 cases of chromophobe cell renal carcinoma were analysed.The average of oncocytoma was 58.8 years old(23～74),and mean tumor size was 5.1 cm(range,3～7 cm);The mean age of chromophobe cell renal carcinoma was 54.5 years old(35～72),and mean tumor size was 5.8 cm(range,3～8 cm).Doppler ultrasonography and CT scan were performed in all patients.All cases accepted surgical operation and were confirmed by pathology.Results Renal oncocytoma was characterized by homogeneous round cell containing aboundant axyphil pellets.Color Doppler ultrasonography show isoechoic or hypoechoic masses.CT scan revealed that the tumors were homogeneous solid masses,and most of them were visualized as homogeneous enhancement.All the patients were followed up for 10 to 53 months,and no recurrence or metastasis was noted.Color Doppler ultrasonography show mainly hyperechoic masses,CT scan revealed most of the tumors were heterogeneous enhancement.All the patients were followed up for 12 to 49 months,and 1 case died from metastasis after 1 year.Conclusion Renal oncocytoma and chromophobe cell renal carcinoma can be differentiated by clinical characteristic,ultrasonic and CT scan examination.The diagnosis is confirmed by pathology.Partial nephrectomy is good for renal oncocytoma,while radical nephrectomy is still the first choice for chromophobe cell renal carcinoma.
