Association analysis of XRCC1-Arg399Gln polymorphism with thyroid-associated ophthalmopathy in Zhuang ethnic population
- VernacularTitle:DNA修复基因XRCC1-Arg399Gln多态位点与壮族甲状腺相关眼病的相关性分析
- Author:
Wenhao MA
;
Rui QIN
;
Shaokang TENG
- Publication Type:Journal Article
- Keywords:
thyroid-associated ophthalmopathy(TAO);
XRCC1;
genetic polymorphism
- From:
Basic & Clinical Medicine
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate potential association of XRCC1-Arg399Gln polymorphism with hyroid-tassociated ophthalmopathy(TAO).Methods XRCC1-Arg399Gln polymorphism was identified by PCR-RFLP in 182 patients with TAO and 182 healthy subjects.Results The significant difference of the allelic frequency distribution was found between TAO and control group(P
