Separation and purification of panaxynol from supercritical CO_2 fluid extraction of panax notoginseng using RP-HPLC

VernacularTitle:反相高效液相色谱法分离纯化三七超临界二氧化碳萃取物中人参炔醇
Author: Yirong FENG ; Xianchun DUAN ; Lunzhun XIA
Publication Type:Journal Article
Keywords: Panaxynol; Chromatography,supercritieal fluid
From: Chinese Journal of Primary Medicine and Pharmacy 2010;17(8):1009-1011,后插1
CountryChina
Language:Chinese
Abstract: Objective To develop a method for the separation and preparation panaxynol. Methods Panax Notoginseng was extracted by SEF-CO_2, and absorbed by silica gel to remove most of the polar impurities. Panaxynol was preparated with RP-HPLC. Result Panaxynol was identified by UV、IR、MS、NMR,and the purity of panaxynol reached 98%. Conclusion The developed method is simple, reproducible and easy to operate. The solvent is cheap,with low boiling point and easy to recovery property.