Drug Resistance and Gene Distribution of Klebsiella pneumoniae Producing the Ultra-broad Spectrum Beta-lactam Enzyme
- VernacularTitle:产超广谱?-内酰胺酶肺炎克雷伯菌的耐药特点与基因型分析
- Author:
Xiaomei LAI
;
Lin LI
;
Youneng GUO
;
Jia FANG
;
Youmei XU
;
Xiangchun FU
;
Wei TANG
- Publication Type:Journal Article
- Keywords:
Klebsiella pneumoniae;
Ultra-broad spectrum beta-lactam enzyme;
The drug resistance;
Gene
- From:
Chinese Journal of Nosocomiology
2009;0(18):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the epidemic,drug resistance and gene distribution of ESBLs-producing Klebsiella pneumoniae (KPN) from Jiangxi TCM Hospital. METHODS The susceptibility of KPN was detected by MIC PCR was used to detect ESBLs gene. RESULTS There were 42 strains with ESBLs isolated,the positive rate was 35.0%. The drug resistance rate of KPN with ESBLs was higher than that without ESBLs,PCR typing result:TEM 33 (78.6%),SHV 8 (19.0%) and CTXM 29 (69.0%). CONCLUSIONS The ESBLs-producing bacteria have multiple drug resistant genes;TEM and CTXM are the main drug resistant genes in our hospital.
