Clinical Distribution and Analysis of Drug Resistance of 554 Enterococcus Isolated
- VernacularTitle:554株肠球菌属的临床分布及耐药性分析
- Author:
Qunying CHEN
- Publication Type:Journal Article
- Keywords:
Enterococcus;
Resistance surveillance;
Antimicrobial agents
- From:
Chinese Journal of Nosocomiology
2009;0(18):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the drug resistance of 554 Enterococcus isolated in our hospital. METHODS The clinical isolates were identified and antimicrobial susceptibility tests were detected by VITEK-60 of Bio-Merieux of France. RESULTS Totally 554 Enterococcus strains were isolated,including 361 E. faecalis (65.2%),143 E. faecium (25.8%),22 E. gallinarum (4.0%),18 E. aviums (3.2%) and 10 other Enterococcus isolates (1.8%). For E. faecalis,the resistance rates to ampicillin and penicillin were lower than the average,(1.1% and 5.3%),which can be chosed as the first selective drugs in clinical therapy for E. faecium,the resistance rates to ampicillin and penicillin both were over 74%,they should be carefully used in therapy. but quinupristin/dalfopristin and linezolid were the best choice.Curing infections caused by the other Enterococcus except E. faecalis and E. faecium,linezolid should be the first selective drug in clinical therapy. CONCLUSIONS While curing infections caused by multi-resistant Enterococcus,doctors should choose proper therapy and according to difference of their drug resistance among Enterococcus spp,in order to prevent appearance of drug-resistant bacteria.
