Molecular abnormality of cardiocyte mitochondrial membrane in diabetic cardiomyopathy
- VernacularTitle:糖尿病心肌病心肌线粒体膜分子异常的研究进展
- Author:
Xiang TANG
;
Shisen JIANG
- Publication Type:Journal Article
- Keywords:
Diabetic cardiomyopathy;
Mitochondrial membrane fluidity;
Mitochondrial permeability transition pore;
Transmembrane potential
- From:
Journal of Medical Postgraduates
2003;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Diabetic cardiomyopathy is one of the main causes of death in diabetic patients.Mitochondrial dysfunction plays a key role in the development of diabetic cardiomyopathy,and mitochondrial function depends on the stabilization of the mitochondrial membrane structure.Studies on the molecular alteration and the underlying mechanism of the cardiocyte mitochondrial membrane of the diabetic heart may give us deeper insights into diabetic cardiomyopathy,and help us make a breakthrough in the therapeutic strategies.