Study on loss of OprD_2 in imipenem-resistant Pseudomonas aeruginosa
- VernacularTitle:耐亚胺培南铜绿假单胞菌OprD_2基因缺失的研究
- Author:
Hongdeng XIA
;
Yuanhong XU
;
Jilu SHEN
;
Tao LI
- Publication Type:Journal Article
- Keywords:
Pseudomonas aeruginosa;
imipenem resistance;
OprD2 gene
- From:
Chinese Journal of Clinical Laboratory Science
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the loss of outer membrane protein D2 (OprD2) gene in imipenem-resistant Pseudomonas aeruginosa.Methods The minimal inhibitory concentrations (MIC) of 10 antimicrobial agents against 80 strains of imipenem-resistant clinical isolates were determined by agar dilution method.PCR was used to detect OprD2 gene.Results PCR results showed that 44 of the 80 isolates of imipenem-resistant P.aeruginosa were positive for OprD2 gene.There was significant difference (P
