Hepatitis B Virus preS1-antigen HBV-DNA,and HBV Markers in Patients with Hepatitis B:Correlation Studies
- VernacularTitle:乙型肝炎病毒前S1抗原与HBV-DNA水平和HBV血清标志物的相关性分析
- Author:
Hongsong MA
;
Zhonghai SHEN
;
Yan JIANG
;
Xiaolan YANG
;
Qilong LIN
- Publication Type:Journal Article
- Keywords:
Hepatitis B Virus preS1-antigen;
HBV-DNA;
HBV markers
- From:
Chinese Journal of Nosocomiology
2009;0(17):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the correlations on hepatitis B virus(HBV)preS1-antigen(preS1-Ag)and HBV-DNA,HBV markers in patients with hepatitis B.METHODS The markers,preS1-Ag and HBV-DNA were determined by ELISA and PCR in 406 patients with hepatitis B and 80 healthy persons.RESULTS The positive rates of preS1-Ag in 160 patients with HBsAg(+)and HBeAg(+)were 84.4%.The positive rates of preS1-Ag in 246 patients with HBsAg(+)and HBeAg(-)were 42.3%;the difference between them was significant(?2=70.9,P
