Pathogens of Nosocomial Infection in Pediatric Patients with Hematologic Malignancy
- VernacularTitle:血液肿瘤患儿医院感染病原菌调查与分析
- Author:
Yi YU
;
Yijin GAO
;
Yi YANG
;
Fengjuan LU
- Publication Type:Journal Article
- Keywords:
Hematologic malignancy;
Nosocomial infection;
Pathogen;
Drug resistance;
Children;
Retrospective study
- From:
Chinese Journal of Nosocomiology
2009;0(17):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the pathogenic distribution and drug resistance of nosocomial infection occurred in pediatric patients with hematologic malignancy and therefore provide the information in rational administration of antibiotics to pediatric patients with hematologic malignancy complicated with nosocomial infection.METHODS Flora cultivation and isolation were operated with the routine methods and drug-sensitivity was determined by Kirby-Bauer method.RESULTS Totally 116 strains of pathogenic bacteria were isolated,in which included 78 strains of G-bacteria and 38 strains of G+ bacteria.Fungi were also very common.In this study,both G-and G+ bacteria were resistant to antimicrobial agents tested.CONCLUSIONS The bacterial spectrum and their drug-resistance characteristics in pediatric patients with hematologic malignancy are quite different to that encountered in pediatric patients with other systemic diseases.Most strains present high resistance to antibiotics,so our administration of antibiotics for nosocomial infections should be directed and carry out according to the susceptibility tests in different area and different periods.
