Modulating factors in the differentiation of stem cells:Present research and progress
- VernacularTitle:干细胞分化及调控因素:近期研究与进展
- Author:
Jing ZHU
;
Xinyi WU
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2007;0(36):-
- CountryChina
- Language:Chinese
-
Abstract:
Stem cell is a kind of cells characterized by self-renewal and multi-differentiation potential;its committed differentiation is the basis of development,growth and renewal in organisms.Recently interest in controlling the differentiation of stem cells is rapidly increasing.The common modulating factors in stem cell differentiation include transcription factors,growth factors and intercellular interactions mediated by membrane proteins.It is shown that the expression level of transcription factors may have important influence on the control,maintenance and recovery of stem cell properties.The latter two factors,growth factors and intercellular interactions,may play a key role in modulating the directional differentiation of stem cells exogenously.This review mainly introduces current research status about those modulating factors in stem cell differentiation.
