Determination of serum HER2 in breast cancer patients and its clinical significance
- VernacularTitle:乳腺癌患者血清HER2的检测及其临床意义
- Author:
Fan WU
;
Yunbin YE
;
Lili LU
;
Qiang CHEN
- Publication Type:Journal Article
- Keywords:
breast neoplasms;
histological HER2 status;
serum HER2
- From:
Chinese Journal of Cancer Biotherapy
1996;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study HER2 levels in the serum and breast cancer tissues and their correlation with clinical parameters,so as to explore drugs selection and prognosis prediction of breast cancer.Methods: Sixty-seven pathologically-confirmed breast cancer patients,20 patients with breast benign tumor,and 20 healthy women,who were treated in Fujian tumor hospital from Jan.2008 to Oct.2008 were included in this study.Expression of HER2 in breast cancer tissues was examined by immunohistochemistry,and serum HER2 level in breast cancer patients was examined by ELISA.Results: Serum level and positive rate of serum HER2 in breast cancer patients were significantly higher than those in healthy women and breast benign tumor patients(P
