Advances ion chitosan sustained-release microspheres containing fluoroquinolones
10.3760/cma.j.issn.1673-4181.2009.06.007
- VernacularTitle:壳聚糖载氟喹诺酮类药物缓释微球的研究进展
- Author:
Peng CHENG
;
Jing GUAN
;
Hua ZHANG
- Publication Type:Journal Article
- Keywords:
Chitosan;
Fluoroquinolones;
Microsphere;
Sustained-release;
Nanoparticles
- From:
International Journal of Biomedical Engineering
2009;32(6):344-347,352
- CountryChina
- Language:Chinese
-
Abstract:
Chitosan microsphere containing fluoroquinolones is a kind of novel sustained-released antibacterial agent that possesses the antibacterial and bacteriostatic property of chitosan as well as bactericidal properties of fluoroquinolones. Loading fluoroquinolones in the chitosan microsphere can greatly enhance its antibacterial, bactericidal, anti-inflammation and anti-infection characteristics. This paper reviewes the recent study on different preparation methods of chitosan mierosphere containing fluoroqninolones and discusses its applications.