Effect of catheter ablation for persistent atrial fibrillation in patients with left ventricular dysfunction
- VernacularTitle:导管消融治疗持续性心房颤动伴左室功能不全的临床评价
- Author:
Yumin SUN
;
Xu LIU
;
Jun WANG
- Publication Type:Journal Article
- Keywords:
Atrial fibrillation;
Heart failure,congestive;
Catheter ablation;
Pulmonary vein
- From:
Chinese Journal of Interventional Cardiology
1996;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical efficacy and safety of catheter ablation for persistent atrial fibrillation in patients with left ventricular dysfunction.Methods Thirty consecutive patients with symptomatic left ventricular dysfunction and left ventricular ejection fraction less than 45 percent underwent catheter ablation for persistent atrial fibrillation were enrolled.Sixty patients mathched according to age,sex,left atrial diameter and duration of atrial fibrillation but without left ventricular dysfunction were selected as the control.All patients underwent circumferential pulmonary vein isolation(CPVI) combined with ablation guided by complex fractionated atrial electrograms(CFAEs).Both parameters correlated with catheter ablation and complications in patients with left ventricular dysfunction were compared will the control.Left ventricular function and left atrial dimension at baseline and at 3 and 9 months after the ablation were evaluated by echocardiogram.Results The ablation procedurts were successful in all patients.The rate of pulmonary vein isolation,ablation time,X-ray exposure time and complications were not significantly different between the left ventricular dysfunction group and the control group(96.67% vs 98.33%,P=1.00;202.23?39.03 min vs 201.87?36.80 min,P=0.97;26.80?7.77 min vs 27.06?7.16 min,P=0.88;3.3% vs 3.4%,P=1.00).After a mean follow up of 11?1 months,73% of the patients with left ventricular dysfunction and 78% of the control remained in sinus rhythm(P=0.61).Forty percent of the left ventricular dysfurction group and 42% of the control received re-ablation respectively.Patients with left ventricular dysfunction showed significant improvement in left ventricular function(increase in ejection fraction by 7.87?4.72%,P
