Evaluation of measurement uncertainty for the determination of ethanol in human blood by auto-headspace GC/MS
- VernacularTitle:自动顶空GC/MS测定血液中乙醇含量不确定度评定
- Author:
Zhifeng ZHOU
;
Ande MA
;
Lingyun CHEN
;
Mei SHEN
;
Fei ZOU
- Publication Type:Journal Article
- Keywords:
forensic toxicological analysis;
measurement uncertainty;
auto-headspace GC/MS;
ethanol
- From:
Chinese Journal of Forensic Medicine
2010;25(1):43-45,47
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the measurement uncertainty for the determination of ethanol in human blood by auto-headspace GC/MS.Methods Each source of uncertainty,arising from the procedure of testing,was analyzed and confirmed according to the guidelines of the uncertainty in measurement.After each uncertainty component was evaluated,the combined standard uncertainty and the expanded uncertainty of the result were calculated.Results The expanded uncertainty was 0.084mg/mL when the concentration of ethanol in blood sample was 0.738 mg/mL.Conclusion The measurement uncertainty of the concentration of ethanol was came primarily from the sample determination,standard solution of the ethanol and the calibration curve.
