Morphology of elderly people's periodontal ligament cells attached to the three-dimensional porous nano-hydroxylapatite
- VernacularTitle:老年人牙周膜细胞附着于纳米-羟基磷灰石上的形态学观察
- Author:
Zhao MAO
;
Ying YIN
;
Xi MAO
;
Chenglin CHU
- Publication Type:Journal Article
- Keywords:
Elderly people;
Periodontal ligament cells;
Three-dimensional porous nano-hydroxylapatite scaffold;
Periodontal tissue engineering
- From:
Journal of Medical Postgraduates
2003;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:Because of the lower proliferation ability of periodontal ligament cells of elderly people,how to choose suitable scaffold materials for them becomes very important.The aim of this study was to observe the morphological manifestation of the periodontal ligament cells of elderly people seeded onto the three-dimensional porous nano-hydroxylapatite scaffolds.Methods: Periodontal ligament cells from elderly people were seeded onto the three-dimensional porous nano-hydroxylapatite scaffolds,cultured for 15 days in vitro,and observed for the morphological changes by scanning electron microscopy in comparison with those of young people.Results:Fifteen days after seeded on the three-dimensional porous nano-hydroxylapatite scaffolds,the periodontal ligament cells of the elderly people exhibited sufficient adhesive behavior,proliferated well and produced tiny calcium nodules,but the number of the nodules was smaller than that in the young people.Conclusion: The periodontal ligament cells of elderly people grow well on three-dimensional porous nano-hydroxylapatite scaffolds,and can be considered as a suitable scaffold for periodontal tissue engineering in elderly people.
