Antiviral Activity Action of Shenghuangketong Ointment
- VernacularTitle:升黄克痛软膏体外抗病毒实验研究
- Author:
Jie YANG
;
Xiqiu ZHAO
;
Sujun GU
- Publication Type:Journal Article
- Keywords:
Shenghuangketong Ointment;
HSV;
Anti-viral action;
In vitro experiment
- From:
Chinese Journal of Nosocomiology
2009;0(15):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the inhibiting effect of Shenghuangketong Ointment on the herpes simplex virus(HSV)-Ⅰ and HSV-Ⅱ. METHODS Histocyte cultivation and cytopathic effect(CPE) were used to examine the inhibiting effect on the HSV-Ⅰ and HSV-Ⅱ. RESULTS EC 50 of Shenghuangketong Ointment on the HSV-Ⅰ and HSV-Ⅱ for HEP-2 cells was 0.94-1.12 mg/ml and 0.94 mg/ml,therapentic index(TI) was 4.0～4.7 and 4.7,respectively. CONCLUSIONS The Shenghuangketong Ointment has inhibiting effect on the HSV-Ⅰ and HSV-Ⅱ.
