?-Lactamases associated Genes of Multi-resistant Pseudomonas aeruginosa in Guangzhou
- VernacularTitle:多药耐药铜绿假单胞菌?-内酰胺类耐药基因研究
- Author:
Cha CHEN
;
Bin HUANG
;
Kai LAN
;
Xueyun PANG
;
Zuhuang MI
- Publication Type:Journal Article
- Keywords:
Pseudomonas aeruginosa;
?-Lactamase;
Resistant genes
- From:
Chinese Journal of Nosocomiology
2009;0(15):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate ?-lactamases genes in multi-resistant Pseudomonas aeruginosa in Guangzhou. METHODS We collected 22 P.aeruginosa strains from hospitalized patients,and detected eleven types of ?-lactamases associated genes by PCR. RESULTS CARB,IMP,TEM,VEB and VIM showed positive amplifications with positive proportions were 100.0%,95.5%,77.3%,13.6% and 4.5%,respectively.Other genes such as GIM,SPM,GES,PER,DHA,OXA-10 and SHV showed negative results. CONCLUSIONS The genes CARB and IMP have high positive rate.Different types of ?-lactamases associated genes in P.aeruginosa aften lead to multi-resistance to antibiotics,which bring great difficulties to clinical therapy and hospital infection monitoring.
