Antibiotics Susceptibility Analysis of Sixty-two Clinical Streptococcus pneumoniae Isolates
- VernacularTitle:临床分离62株肺炎链球菌的分布及耐药性分析
- Author:
Gangsen ZHENG
;
Xiuyu SONG
;
Chaoyang HUANG
;
Xiaobo MA
- Publication Type:Journal Article
- Keywords:
Streptococcus pneumoniae;
Antibiotics susceptibility test;
Resistance
- From:
Chinese Journal of Nosocomiology
2009;0(15):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the in vitro antimicrobial susceptibility of Streptococcus pneumoniae and guide the rational use of drug clinically. METHODS We performed statistical analysis of the susceptibility of 62 strains of S.pneumoniae isolated in our hospital from May 2007 to Aug 2008. RESULTS S.pneumonia e could be isolated from various specimens,most of them were isolated from sputum(84.0%).S.pneumoniae could be detected from many hospital wards,but more strains isolated from pediatric(67.8%) and respiratory(11.4%) departments.A total of 67.7% of S.pneumoniae isolates were penicillin non-susceptible,the resistance prevalence to tetracycline was 87.1%,to erythromycin 79.0% and to trimethoprim/sulfamethoxazole 49%,while they were highly susceptible to ofloxacin(90.3%),vancomycin(91.9%),levofloxacin(95.2%),moxifloxacin(96.8%) and rifampicin(98.4%),and more strains showed multi-resistance from penicillin non-susceptible isolates. CONCLUSIONS The resistance to penicillin of S.pneumoniae is serious in our hospital.The tetracycline and erythromycin are not the best ckoice in treating S.pneumoniae infection,and the new fluroquinolones show strong activity against S.pneumoniae.
