Glargine combined with glimepiride for diabetes in elderly patients
- VernacularTitle:甘精胰岛素联合格列美脲治疗老年糖尿病的疗效观察
- Author:
Ping GU
;
Xiaoqian CHEN
;
Yamei WANG
- Publication Type:Journal Article
- Keywords:
Glargine;
Glimepiride;
Neutral protamine hagedorn insulin;
Elderly patient
- From:
Journal of Medical Postgraduates
2003;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: Insulin glargine is a new long-acting basal insulin analogue.Glimepiride is an anti-diabetic drug with action independent of the pancreas.In this study,the efficacy and safety of glargine plus glimepiride in the treatment of elderly diabetic patients were evaluated.Methods: Sixty-five elderly diabetic patients were randomly assigned to receive Neutral protamine hagedorn insulin(NPH) plus glimepiride(n=19),and glargine plus glimepiride(n=21).The dose of insulin was adjusted according to the fasting blood glucose(FBG) level,with the target FBG