Effect of Herbal Tanreqing-injection Combined with Vancomycin in Treatment of MRSA Pneumonia and Antibiotic Resistance of the pathogens
- VernacularTitle:痰热清与万古霉素治疗耐甲氧西林金黄色葡萄球菌性肺炎及其耐药性研究
- Author:
Zhixiang SONG
;
Wei LU
;
Liang CHEN
;
Shuang WANG
;
Xingguang LI
- Publication Type:Journal Article
- Keywords:
MRSA;
Resistance to antibiotic;
Pneumonia;
Tanreqing-injection;
Vancomycin
- From:
Chinese Journal of Nosocomiology
2009;0(14):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate(meticillin-resistant Staphylococcus aureus MRSA) the antibiotics resistance and curative effect of herbal Tanreqing-injection combined with vancomycin in the treatment of MRSA pneumonia.METHODS All data of microbiology about sputum culture between 2001-2007 were statistically analyzed with a retrospective method in a hospital,in order to understand the MRSA prevalence trends and their resistance.From 100 cases of MRSA pneumonia,50 cases were treated by vancomycin alone,another 50 cases were treated by Tanreqing injection plus vancomycin.RESULTS There were 3082 MRSA strains and 162(meticillin-sensitive S.aureus MSSA) strains in 3244 S.aureus strains;nosocomial infection cases accounted for 78.07% in MRSA-positive sputum samples;MRSA wasn't resistant to vancomycin,but resistant to other antibiotics.Resistance rates had a significant difference between MRSA and MSSA(P