Analysis of proteomics of seminal plasma from male patients with idiopathic infertility
- VernacularTitle:特发性男性不育患者精浆蛋白质分析
- Author:
Xuyi REN
;
Minlan ZHOU
;
Xinzong ZHANG
;
Yang LIU
;
Runliu YU
- Publication Type:Journal Article
- Keywords:
idiopathic male infertility;
seminal plasma;
two-dimensional electrophoresis
- From:
Basic & Clinical Medicine
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discover biological markers of male infertility.Methods Two-dimensional electrophoresis and Mass-Spectrum techniques(MS+MS/MS) were used for analyzing the seminal plasma from idiopathic male infertility and the control.Results Serum albumin and prostatic acid phosphatase were reduced in seminal plasma from idiopathic male infertility,while Cathepsin B and Zn-alpha-2-glycoprotein were increased.ConclusionIdiopathic male infertility was potentially associated with disorder of sperm capacitation and seminal immune function.
