Analysis of Plant TATA and TATA-less Promoters by Using Sequence and Structure Features
- VernacularTitle:基于序列和结构特征分析植物TATA和TATA-less启动子
- Author:
Yongchun ZUO
;
Qianzhong LI
- Publication Type:Journal Article
- Keywords:
plant pol-Ⅱ promoter, features of sequence content bias, TATA and TATA less promoter, conservative motifs, position-correlation weight matrix(PCWM)
- From:
Progress in Biochemistry and Biophysics
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Analysis of regular elements in promoter region is the base for elucidating the mechanism of gene transcription initiation.The TATA and the TATA-less promoters of plant RNA polymerase Ⅱ gene are chosen from the PlanPromDB.The GC bias,position structure conservation,nucleotide content and conservative motifs of sequences,position distribution of TATA box and conservation of correlation position are analyzed.Many specific regulars for the two types of promoters are found.These features can offer some help for revealing the transcription regulation of plant gene.A new prediction algorithm based on position-correlation weight matrix(PCWM) is proposed.The better discrimination results for two sort plant promoters are obtained by using score function.It is confirmed that the performance of position-correlation weight matrix(PCWM) is superior to single-base position weight matrix(PWM).
