Expression of Ets-1 and VEGF in breast invasive ductal carcinoma and its clinical significance
- VernacularTitle:Ets-1、VEGF在乳腺浸润性导管癌组织的表达及其临床意义
- Author:
Tao LIU
;
Jingchuan ZHANG
;
Jingsheng HE
- Publication Type:Journal Article
- Keywords:
breast invasive ductal carcinoma;
Ets-1;
VEGF;
immunohistochemistry;
RT-PCR
- From:
Chinese Journal of Cancer Biotherapy
1995;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the expression of Ets-1 and VEGF in breast invasive ductal carcinoma (IDC) tissues,and to analyze its correlation with clinicopathologic characteristics of IDC. Methods:Forty breast IDC tissues and their adjacent normal tissue samples were obtained from clinical diagnosed breast IDC patients after surgery. Expression of Ets-1 and VEGF protein and mRNA was examined by immunohistochemistry and RT-PCR. Results:(1)Expression of Ets-1 and VEGF protein in breast IDC tissues was significantly higher than that in adjacent normal tissues (P