Clinical characteristics of central hyponatremia
- VernacularTitle:中枢性低钠血症的临床特点
- Author:
Xucai CHEN
;
Lihua LIU
;
Guocheng WANG
- Publication Type:Journal Article
- Keywords:
central hyponatremia;
syndrome of inappropriate ADH secretion;
cerebral salt wasting syndrome
- From:
Journal of Clinical Neurology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clincal characteristics of central hyponatremia.Methods The clinical data of 34 patients with central hyponatremia were analysed retrospectively.Results 34 patients with different cerebral diseases appeared dysphoria,sleepiness,aggravating disturbances of consciousness,vomiting,limb seizures and dehydration basis on primary diseases during the hospitalization.The laboratory examinations showed that the level of blood natrium was 260 mmol/d in all the cases,and the central venous pressures in 5 cases were lower than 6 cm H2O among 8 cases.The 19 cases were diagnosed as central hyponatremia——syndrome of inappropriate ADH secretion(SIADH);7 cases were diagnosed as central hyponatremia——cerebral salt wasting syndrome(CSWS).The other 8 cases were diagnosed as SIADH firstly,but final diagnosis were corrected as CSWS according to the symptoms increasing after dehydration therapy.The 19 case of SIADH received the therapy of limiting water and diuresis,and 15 cases of CSWS received the therapy of hydration and supplementing sodium.The several days after the treatment,the levels of the blood natrium and the urinary natrium were backed to the normal values in all the patients and the condition was improved exapet 3 cases remained coma.Conclusions Hyponatremia,hypernatruria and changes of consciousness are the clinical charateritics of central hyponatremia.The treatment principle in SIADH is limiting water,and in CSWS is hydration and supplementing sodium.
