Effects of intervention with Simvastatin and Aspirin on carotid artery atherosclerosis
- VernacularTitle:辛伐他汀及阿司匹林干预对颈动脉粥样硬化的影响
- Author:
Jinshu ZHENG
;
Qingyin WANG
;
Qingzhu WANG
- Publication Type:Journal Article
- Keywords:
carotid artery atherosclerosis;
Simvastatin;
Aspirin
- From:
Journal of Clinical Neurology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effects of intervention with Simvastatin and Aspirin on carotid artery atherosclerosis(CAA).Methods 120 patients with ischemic cerebrovascular disease and complicated CAA and blood-lipid abnormality were randomly divided into the Simvastatin group,Aspirin group,Simvastatin+ Aspirin group.Each group received corresponding therapy for 6 months.The changes of serum C-reactive protein(CRP) level,blood-lipid level,the carotid artery intimal and media thickness(IMT),the plaque areas before and after treatment and the recurrence rate of cerebrovascular event among the 3 groups were compared.Results Compared with before treatment,the levels of serum CRP were significantly decreased in the 3 groups after treatment(all P
