Updated correlation of the protein kinase C family with cancer
- VernacularTitle:蛋白激酶C家族与肿瘤相关性研究进展
- Author:
Yanqiang SHAO
;
Yun SU
;
Maoyin YAO
- Publication Type:Journal Article
- Keywords:
Protein kinase C;
Cancer;
Signal transduction
- From:
Journal of Medical Postgraduates
2003;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Protein kinase C(PKC) is the main signaling molecule of the diacylglycerol dependent protein kinase C signal transducting system.PKC plays an important role in the generation and progress of cancer.The activation of PKC is associated with the proliferation,differentiation,apoptosis,migration and multidrug resistance(MDR) of tumor cells.It may become a novel anti-tumor strategy to block the proliferation and drug resistance signal transduction passageways with new specific PKC inhibitors directed at the PKC subgroup in tumor cells.
