Investigateion of Death Cases Infected by MRSA and Their Drug-resistance
- VernacularTitle:耐甲氧西林金黄色葡萄球菌感染死亡病例调查及耐药分析
- Author:
Yanhua ZHANG
;
Huiling WEI
;
Changying GUO
;
Xin CHEN
- Publication Type:Journal Article
- Keywords:
MRSA;
Nosocomial infection;
Drug resistance
- From:
Chinese Journal of Nosocomiology
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the hospital acquired MRSA infection death cases and drug-resistance to improve the proper clinical utilization of antibiotics.METHODS The clinical data of the death cases in ICU wards from Mar 2008 to Jun 2008,and the drug sensitivity and resistance results of MRSA from Jan 2007 to Dec 2008 were analyzed retrospectively.RESULTS MRSA isolated from all of the three death cases were susceptible to vancomycin and unsusceptible to other antibiotics.Thirty MRSA strains were isolated from Jan 2007 to Dec 2008.Drug sensitivity test showed 100% drug-resistance rate to penicillin,erythromycin,cefazolin and oxacillin;66.7%-87.0% drug-resistance rate to ciprofloxacin,clindamycin,levofloxacin,and sulfamethoxazole compound.CONCLUSIONS High drug-resistance rate of MRSA to commonly used antibiotics is found.MRSA is usually infected in patients with malnutrition,major surgery or infants long term using ventilator.Sensitive antibiotics should be used in early time and regulations from aspects of hospital infection control,medical administration and nursing management also be carried out to prevent and control the prevalence of MRSA bacteria.
