Efficacy of Lamivudine on Prevention of Liver Injury in HBV Carriers Complicating Tuberculous Pleurisy after Use of Antituberculosis
- VernacularTitle:拉米夫定预防乙型肝炎合并结核性胸膜炎抗结核治疗致肝损伤疗效观察
- Author:
Yonghua ZHAO
;
Jinjiang MU
;
Jianwu YU
;
Shuchen LI
- Publication Type:Journal Article
- Keywords:
Lamivudine;
Hepatitis B virus;
Tuberculous exudative pleurisy
- From:
Chinese Journal of Nosocomiology
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To evaluate the clinical efficacy of lamivudine on prevention of liver injury in HBV carriers complicating tuberculous exudative pleurisy after use of antituberculosis drugs.METHODS Totally 120 HBV carriers complicating tuberculous exadative pleurisy after use of antituberculosis drugs were randomly divided into lamivudine group and control group.RESULTS The incidence rate of liver injury was 10.0% in lamivudine group vs 1.7% in control group(P0.05).CONCLUSIONS Lamivudine may be good for reducing liver injury in HBV carriers complicating tuberculous exadative pleurisy after use of antituberculosis drugs.
