Incidence and Drug-Resistance of Helicobacter pylori from Patients with Peptic Ulcer
- VernacularTitle:消化性溃疡幽门螺杆菌的分离培养及耐药分析
- Author:
Honglei SONG
;
Huiqin ZHOU
;
Huan YANG
;
Xueming ZHU
- Publication Type:Journal Article
- Keywords:
Peptic ulcer disease;
Helicobacter pylori;
Drug sensitive test
- From:
Chinese Journal of Nosocomiology
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate incidence and drug susceptibility of Helicobacter pylori(Hp) in local area.METHODS Strains of Hp were isolated and cultivated from gastric antrum mucosa of 141 peptic ulcer disease(PUD) patients diagnosed by gastroscope.The drug sensitive test of Hp strains was examined by K-B method.RESULTS The isolation rate of Hp in 141 PUD patients was 75.2%.Hp isolates showed a relative hypersensitivity to clinical commonly used drugs(ie furazolidone,amoxicillin,levofloxacin,cefuroxime and moxifloxacin).On the other hand,Hp isolates exhibited resistance to metronidazole and clarithromycin.CONCLUSIONS Hp is an important etiologic factor of PUD,and showing an increasing resistance to common clinical antibiotics.
