Safety of Superselective Transcatheter Arterial Chemoembolization through Cystic Artery for Treatment of Hepatocellular Carcinoma.
10.3348/jkrs.2001.44.1.37
- Author:
Jae Ho BYUN
1
;
Hyun Ki YOON
;
Ho Young SONG
;
Deok Hee LEE
;
Jae Cheol HWANG
;
Bong Soo KIM
;
Jae Won KIM
;
Kyu Bo SUNG
Author Information
1. Department of Diagnostic Radiology, Asan Medical Center,University of Ulsan College of Medicine.
- Publication Type:Original Article
- Keywords:
Liver neoplasms, angiography;
Liver neoplasms, chemotherapeutic embolization;
Hepatic arteries, therapeutic embolization
- MeSH:
Angiography;
Arteries*;
Carcinoma, Hepatocellular*;
Cholecystitis;
Cisplatin;
Ethiodized Oil;
Follow-Up Studies;
Gelatin Sponge, Absorbable;
Humans
- From:Journal of the Korean Radiological Society
2001;44(1):37-42
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To report on the safety and efficacy of superselective transcatheter arterial chemoembolization( TACE) of tumor feeding branches originating from the cystic artery for the treatment of hepatocellular. MATERIALS AND METHODS: From, May 1995 to, September 1999, eleven HCC patients aged between 38 and 82 (mean, 57.4) years with tumor-feeding branches originating from the cystic artery underwent TACE. In eight, for whom superselection of these branches was possible, TACE was done with the use of Gelfoam and a mixture of Lipiodol and cisplatin, while for three, for whom superselection was impossible, a mixture of Lipiodol and cisplatin only was used. Immediately after TACE, remnant tumor staining was angiographically evaluated,and tumor response was determined by follow-up CT at one month. After procedure, the development of cholecystitis was assessed clinically. RESULTS: Post-TACE angiography showed remnant tumor staining in one patient who underwent embolization with Gelfoam and the mixture of Lipiodol and cisplatin, and in one for whom the mixture of Lipiodol & cisplatin only was used. Among the eight for whom Gelfoam and the mixture of Lipiodol and cisplatin was used,one-month follow-up CT showed compact Lipiodol uptake in five, partial Lipiodol uptake in three, no change in tumor size in six, increased tumor size in one, and decreased tumor size in one. Among the three for whom the mixture of Lipiodol and cisplatin only was used, one-month follow-up CT showed neither Lipiodol uptake nor change in tumor size in one patient, partial Lipiodol uptake and increased tumor size in one, and compact Lipiodol uptake and decreased tumor size in one. Cholecystitis developed in only one patient who underwent embolization with Gelfoam and the mixture of Lipiodol and cisplatin, but was cured by conservative treatment. CONCLUSION: Superselective TACE of tumor feeding branches originating from the cystic artery seems to be a safe and effective method for the treatment of hepatocellular carcinoma.
