Genetic Marker of Class Ⅰ Integron and Transposable Element of Acinetobactor baumannii Isolated from ICU
- VernacularTitle:鲍氏不动杆菌新型整合子、Ⅰ类整合子遗传标记研究
- Author:
Guozhong CHEN
;
Yiping WANG
;
Minfei AN
;
Jianfei YING
;
Yanhong YU
;
Chengjie ZHOU
;
Mingyang HE
- Publication Type:Journal Article
- Keywords:
Acinetobacter baumannii;
Multiple-drug resistance;
Genetic marker;
Transposable element;
Class Ⅰ integron;
Gene qacE△1-sul1
- From:
Chinese Journal of Nosocomiology
2005;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To study the existence status of class Ⅰ integron and transposable element of multi-resistant Acinetobactor baumannii isolated form ICU of Yinzhou People′s Hospital in Ningbo. METHODS The samples of 20 A.baumannii isolates were collected from Oct 2007 to Jul 2008.The susceptibility to 32 antibiotics of the isolates was measured.The genetic markers of integron qacE△1-sul1 and transposable element tnpU were analyzed by polymerase chain reaction(PCR).The PCR products of tnpU or qacE△1-sul1 were sequenced for determination. RESULTS In the 20 ABA isolates,the positive rate of class Ⅰ integron qacE△1-sull was 75%,and the positive rate of transposable element tnpU was 55.0%. CONCLUSIONS The positive rate of the integron qacE△1-sul1 and transposable element tnpU for multi-resistant A.baumannii is high in Yinzhou People′s Hospital in Ningbo.It should be reevaluated the preventative role of chlorhexidine for operation.
