Detection of qacE△1-sul1 in Acinetobacter baumannii Isolated from Xinjiang and Its Clinical Significance
- VernacularTitle:新疆地区鲍氏不动杆菌qacE△1-sul1基因检测及临床意义
- Author:
Jian ZHANG
;
Zhenhong ZHU
;
Guanglong SU
;
Ping JI
- Publication Type:Journal Article
- Keywords:
Acinetobacter baumannii;
Resistant bacilli;
qacE△1-sul1 gene
- From:
Chinese Journal of Nosocomiology
2005;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To study the antibiotic resistance gene of qacE△1-sul1 in Acinetobacter baumannii isolated from inpatients in Urumqi and the distribution and difference of qacE△1-sul1 genotype in Xinjiang. METHODS Bacterial strains were identified by system of API and antibiotic susceptibility test was detected by K-B and microdilution methods according CLSI.PCR was used to determine the gene of qacE△1-sul1 and compared with the sequences in GenBank. RESULTS Antibiotic resistance phenotypes showed the resistance rate to cefataxime and tetracycline was the highest(100.0%),but that to cefoperazone/sulbactam was the lowest.The positive rate of qacE△1-sul1 gene in A.baumannii was 52.2%. CONCLUSIONS High resistance in A.baumannii is found in Xinjiang.The positive rate of qacE△1-sul1 is high.Strengthening epidemiology surveillance of resistance carried by integron-carrying gene is important.
