Surveillance on MIC of Antibiotic Resistance of Meticillin-resistant Staphylococcus aureus
- VernacularTitle:耐甲氧西林金黄色葡萄球菌对抗菌药物MIC值的监测
- Author:
Lijiang CHEN
;
Tieli ZHOU
;
Qing WU
;
Meina LIU
;
Lianfeng WU
- Publication Type:Journal Article
- Keywords:
MRSA;
Vancomycin;
Teicoplanin;
Linezolid
- From:
Chinese Journal of Nosocomiology
2005;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To review and analyze the change in the MICs of vancomycin,teicoplanin and linezolid in meticillin-resistant Staphylococcus aureus(MRSA) strains isolated in our hospital from 2003 to 2007. METHODS The MICs of vancomycin,teicoplanin and linezolid were tested by Etest method on a sample of randomly selected MRSA strains. RESULTS The incidences of MRSA increased from 52.2% in 2003 to 74.5% in 2007.MIC of vancomycin increased from 1.85 ?g/ml in 2003 to 2.15 ?g/ml in 2007,and teicoplanin MIC geometric mean increased even more markedly from 1.28 ?g/ml in 2003 to 2.07 ?g/ml in 2007.The linezolid MIC remained almost unchanged. CONCLUSIONS The incidences of MRSA were increasing from 2003 to 2007.There is a upward trend in MIC of glycopeptide over the years,in which the increase for teicoplanin is higher than others two.
