Changes of homeostatic activation in patients after percutaneous coronary intervention and its relationship with plasminogen activator inhibitor-1 gene polymorphism
- VernacularTitle:冠脉介入治疗后止凝血功能的改变及其与PAI基因多态性的关系
- Author:
Min SUN
;
Jinyi WU
;
Jian HOU
;
Shuangbin LI
- Publication Type:Journal Article
- Keywords:
percutaneous coronary intervention;
polymorphism,single nucleotide;
plasminogen activator inhibitor-1;
GMP-140;
factor Ⅶ;
D-Dimer
- From:
Journal of Jilin University(Medicine Edition)
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05).In the patients with 4G/4G polymorphism of PAI1 gene,the GMP-140,vWF,FⅦa,D-D and PAI-1 levels in plasma were significantly increased at immediate postoperative period(P0.05).In the patients with 4G/5G and 5G/5G genotypes,all indexes mentioned above were significantly increased at immediate postoperative period(P0.05).In the patients with 4G/4G genotype,the PAI-1 level in plasma was significantly higher than those in the patients with 4G/5G and 5G/5G genotypes 24 h after PCI(P
