Voriconazole Therapy of Fungal Infections in Patients with Hematologicy Malignancies
- VernacularTitle:伏立康唑在恶性血液病患者真菌感染中的应用
- Author:
Zhiyong YU
;
Xiaoying ZHANG
;
Botao LI
;
Chen XU
;
Hu CHEN
- Publication Type:Journal Article
- Keywords:
Hematologic malignancies;
Fungal infections;
Voriconazole;
Amphotericin B
- From:
Chinese Journal of Nosocomiology
2004;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To report malignant hematologic patients suffered in fungal infections treated with voriconazole(VOR),compare them with other similar patients treated with aluphotericin B liposome(L-AMB) as control,and then review the references.METHODS Fifty patients were treated with VOR and 57 patients were treated with L-AMB.According to the clinical performance and the changes in the CT,we could find the difference of between them.RESULTS Forty cases were effective in VOR group and most of them were in good tolerance.In the control group,37 cases were effective,most of them were in poor tolerance,and some of them stopped the treatment.CONCLUSIONS Instead of L-AMB,VOR can be a useful drug in the treatment of hematologic malignancies patients suffered in fungal infections.
