Clinical Isolates Caused Hospital Infection in Patients with Hematological Diseases:Their Distribution and Antimicrobial Resistance
- VernacularTitle:血液系统疾病医院感染临床分离菌株分布与耐药性分析
- Author:
Qi DENG
;
Xin LI
;
Jingyi LI
;
Yuming LI
- Publication Type:Journal Article
- Keywords:
Hematological disease;
Hospital infection;
Bacterial resistance
- From:
Chinese Journal of Nosocomiology
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the distribution and antibiotic resistance of isolates from hospitalized patients with hematological disease in 2005-2007.METHODS A total of 431 bacterial strains were isolated from patients with hematological disease from Jan 2005 to Dec 2007.Antimicrobial susceptibility testing was taken by micro-dilution method.RESULTS Among the 364 bacterial strains,170(39.5.7%)were Gram-positive organisms and 194(45.0%) were Gram-negatives.Among the 170 Gram-positive strains,41.2% were enterococci and 6.3% were E.faecium strains.meticillin-resistant Staphylococcus aureus(MRSA) and meticillin-resistant coagulase negative staphylococcus(MRCNS) accounted for 71.4% and 35.8%.No vancomycin resistant Staphylococcus spp and Enterococcus spp were found.The top 5 Gram-negtive species were Escherichia coli,Klebsiella pneumoniae,Pseudomonas aeruginosa,Stenotrophomonas maltophilia and Acinetobacter baumannii.Detection rates of ESBLs in E.coli and K.pneumoniae were 17.5% and 9.1%.Two pan-resistant P.aeruginosa strains were found in 2007.CONCLUSIONS Our data are important and valuable for the rational antimicrobial therapy of infections in patients with hematolagical disease.
