Influence of polyvinylpyrrolidone and hydroxypropyl - beta - cyclodextrine on solubility of dehydro epiandrosterone
- Author:
Nguyen Thanh Hai
- Publication Type:Journal Article
- Keywords:
polyvinylpyrrolidone, hydroxypropyl - beta - cyclodextrine, dehydro epiandrosterone
- MeSH:
Povidone;
beta-Cyclodextrins;
Androsterone
- From:Pharmaceutical Journal
2004;34(11):7-8
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
PVP only does not enhance the solubility of DHEA but a combination effect will manifeste once the substance is used concurrently with HPCD. In 5,59% HPCD solution, this solubility was enhanced by 115 times and in 5,59% HPCD solution adding 0,1% PVP it was enhanced by 139 times. There is a strict interaction between its components, different evidently from the physical mixed graphic
