Antibiotics Resistance of Escherichia coli Inducing Hospital Infection
- VernacularTitle:随州市大肠埃希菌医院感染及耐药性调查分析
- Author:
Bo ZHU
- Publication Type:Journal Article
- Keywords:
Escherichia coli;
Hospital infection;
Drug-resistance;
Extended spectrum ?-lactamases(ESBLs)
- From:
Chinese Journal of Nosocomiology
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate drug-resistance status and changing tendency of Escherichia coli inducing hospital infection to provide the evidence for reasonable use of antibiotics. METHODS Pathogenic bacteria were isolated and identified according to the National Clinical Laboratory Manipulation Rules. Drug resistance profile was analyzed by K-B methods. RESULTS In the four years, the resistance to seventeen common antibiotics in E. coli was on the rise. The resistance rate to ampicillin was the most highest, 90.8-94.2%. There was no strain that was resistant to imipenem and meropenem. Detection rate of extended spectrum ?-lactamases (ESBLs) producing E. coli increased from 13.2% to 32.0%. CONCLUSIONS Drug-resistance status of E. coli inducing hospital infection is very serious. We should strengthen the management of antibiotic use and control the spread and prevalence of the drug-resistant bacteria.