Flora Distribution and Resistance in Nosocomial Pneumonia Caused by Gram-negative Bacilli
- VernacularTitle:革兰阴性杆菌医院肺炎的菌群分布及耐药性调查
- Author:
Jiangyun LU
- Publication Type:Journal Article
- Keywords:
Gram-negative bacilli;
Nosocomial infections;
Bacterial pneumonia;
Drug resistance
- From:
Chinese Journal of Nosocomiology
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate flora distribution and drug resistance status in Gram-negative bacilli nosocomial pneumonia and to provide the scientific reference for clinical correct diagnosis and reasonable use of antibiotics. METHODS Referring to National Clinical Laboratory Manipulation Rules, the strains were isolated and cultured. The strains were identified by routine identification methods.The antibiotic susceptibility test was performed by K-B method and the results were read according to CLSI 2006. RESULTS Among 399 strains of Gram-negative bacilli, the detection rate of Pseudomonas aeruginosa ranked the first (24.1%). Severe drug resistance was found in Gram-negative bacilli. Except for 19.7% Acinetobacter baumannii strains resistant to imipenem and meropenem, drug resistance rate to the other common antibiotics was all more than 50.0%. The detection rate of extensive-spectrum beta-lactamases (ESBLs) producing Klebsiella Pneumoniae and Escherichia coli was 42.4% and 39.2%, respectively. CONCLUSIONS The Gram-negative bacilli pneumonia is mostly caused by drug resistant strains. We should strengthen precaution, monitoring and controlling of them.
