Experimental study on the extraction of total triptolides from lactone leaves with macroporous resin
- VernacularTitle:大孔树脂用于雷公藤叶总内酯提取的研究
- Author:
Shudong WANG
;
Li FANG
;
Hanbao LI
- Publication Type:Journal Article
- Keywords:
Macroporous resin;
Lactone leaves;
Total triptolides;
Extraction process
- From:
Journal of Medical Postgraduates
2003;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: The total triptolides in lactone leaves are generally extracted by decocting with chloroform,which is known to be a poisonous substance and pollutes the environment.The authors aimed to evaluate the use of macroporous resin in the extraction process.Methods: We measured the total triptolides by spectrophotometry and investigated the technology of extracting the total triptolides with macroporous resin,including determination of the concentrations of decoction and alcohol in the alcohol precipitation as well as the consumption of resin.Results: The total triptolides were enriched with the combination method of decoction by alcohol precipitation with macroporous resin.The ratio of concentration medicine to decoction was 1 ∶ 2,and that of the volume proportion of alcohol to decoction in the precipitation of alcohol was 2 ∶ 1.The appropriate amount of resin was 15%.Conclusion: Macroporous resin can be used to extract the total triptolides.
