Cytoprotective effect of nuclear factor erythroid 2-related factor 2-antioxidant response element signaling pathway
- VernacularTitle:转录因子NF-E2相关因子2-抗氧化转录元件信号路径细胞保护作用的研究进展
- Author:
Yaqi SONG
;
Handong WANG
- Publication Type:Journal Article
- Keywords:
Nuclear factor erythroid2-related factor 2;
Antioxidant response element;
Cytoprotection
- From:
Journal of Medical Postgraduates
2003;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Nuclear factor erythroid2-related factor 2(Nrf2) is an important protective transcription factor that generally exists in various organisms and cellules.Normally,it is sequestered in the cytoplasm.Environmental stress can activate its signal factor,lead to its nuclear translocation,and enhance the anti-oxidation,deintoxication and anti-apoptosis function of the organism,for which the Nrf2-antioxidant response element(Nrf2-ARE) signaling pathway is one of the most important protective ones.This article updates the cytoprotective effect of Nrf2-ARE signaling pathway.
