?-Lactamase Genes and Antibiotic Resistance in Escherichia coli
- VernacularTitle:产ESBLs大肠埃希菌?-内酰胺酶基因检测与耐药性分析
- Author:
Xiaomei ZHANG
;
Jianwei PAN
;
Jianjuan WU
;
Jiaping WANG
;
Sujian WANG
- Publication Type:Journal Article
- Keywords:
Escherichia coli;
Resistant genes;
ESBLs
- From:
Chinese Journal of Nosocomiology
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the ?lactamase genes in Escherichia coli and their resistance.METHODS Twenty strains of E.coli producing extended spectrum ?-lactamases(ESBLs) were isolated from hospitalized patients.?-Lactamase drug-resistant genes were detected by PCR.RESULTS There were higher positive rates of ?-lactamase genes of TEM,SHV,LEN,CTX-M-1,CTX-M-9,VEB,GES,PER(75.0%,20.0%,95.0%,15.0%,70.0%,5.0%,85.0% and 70.0%,respectively). This study showed that there were high positive rate of drug resistance.CONCLUSIONS There are very high positive percentages of TEM,LEN,CTX-M-9,GES,and PER genes in ESBLs producing E.coli isolated clinically,and showing highly drug-resistant E.coli of producing ESBLs can be transmitted in hospital and induce fulminant prevalence.
