Granulocyte colony-stimulating factor and hematonosis
- VernacularTitle:粒细胞集落刺激因子与血液病
- Author:
Yujie MA
;
Hui LIANG
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2007;0(14):-
- CountryChina
- Language:Chinese
-
Abstract:
Granulocyte colony-stimulating factor is a glycosylated polypeptide chain cell growth factor that can promote proliferation and differentiation of myeloid progenitors and induce maturation of these cells toward terminally differentiated neutrophils.Granulocyte colony-stimulating factor which functions and effects depend on the combination with specific receptor on the surface of effector cells.With the development of gene cloning technology,ganulocyte colony-stimulating factor recombinant products have been widely used in clinic to provide effective means for the treatment of leucopenia,In recent years,we find the therapy of chemotherapeutics combining with granulocyte colony-stimulating factor is effective in refractory/relapsed/elderly cases of acute leukaemia.Currently,granulocyte colony-stimulating factor is one of important and successful hematopoietic cytokines in clinic.
