Expressions of CD40 and ICAM-1 in primary hepatocarcinoma and clinical significance
- VernacularTitle:CD40与ICAM-1在原发性肝细胞癌组织中的表达及临床意义
- Author:
Yaxin SUN
;
Zhichao ZHANG
;
Mingku JIA
- Publication Type:Journal Article
- Keywords:
primary hepatocarcinoma;
immunohistochemistry;
CD40;
ICAM-1
- From:
Journal of Jilin University(Medicine Edition)
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expressions of CD40 and ICAM-1 in primary hepatocarcinoma and clinical significance and analyze their relationships with carcinogenesis and progression of liver cancer. Methods S-P immunohistochemistry was used to detect the expressions of CD40 and ICAM-1 in 40 cases of hepatocarcinoma and 25 cases of normal liver tissue (distance from cancer tissues≥2 cm).Results The positive expression rates of CD40 and ICAM-1 were 47.5% and 82.5% in liver cancer tissue,which was significantly higher than those in normal liver tissue (P0.05).The positive expression rate of ICAM-1 was associated with lymph node metastasis as well as histological grade(P
