Role of suppressor of cytokine signaling in the regulation of negative feedback in the JAK/STAT signaling pathway
- VernacularTitle:细胞因子信号转导抑制蛋白在JAK/STAT信号通路中的负反馈调节作用
- Author:
Minli LI
;
Renmin ZHU
- Publication Type:Journal Article
- Keywords:
Suppressor of cytokine signaling;
JAK/STAT pathway;
Signal transduction;
Negative feedback
- From:
Journal of Medical Postgraduates
2003;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Suppressors of cytokine signaling (SOCS) associates with receptor-mediated signal transduction pathway,which can regulate cell proliferation,growth,differentiation and inflammation et al. The aim of this review is to identify SOCS and cytokines on the combination of different sites and pathway,and then to explore the pathogenesis of the role of negative feedback regulation of JAK/STAT signaling pathway.
