Detection and Analysis of Integron and Metallo-?-Lactamase in Stenotrophomonas maltophilia
- VernacularTitle:嗜麦芽寡养单胞菌金属酶基因及整合子检测分析
- Author:
Huaimin XIONG
;
Chuandan WAN
;
Jianhua SHENG
;
Chen WU
;
Yinghong CUI
- Publication Type:Journal Article
- Keywords:
Stenotrophomonas maltophilia;
Metallo-?-lactamase;
Integron
- From:
Chinese Journal of Nosocomiology
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To study the existence of integron and metallo-?-lactamase in Stenotrophomonas maltophilia in our hospital.METHODS The antibiotic susceptibility was tested by K-B method.The genomic DNA and their plasmids were extracted.The integron and metallo-?-lactamase gene were amplified by polymerase chain reaction(PCR).RESULTS L1 and L2 genes were amplified in chromosomes and plasmids.Integrons Ⅰ and Ⅱ were detected in genomic DNA.CONCLUSIONS Existence of metallo-?-lactamase is one of reasons of multi-drug resistance in S.maltophilia.S.maltophilia can receive integrons and gain its multi-drug resistance from other strains.