Risk Factors and Infection Characteristics in Patients with Chronic Severe Hepatitis B
- VernacularTitle:慢性重型乙型病毒性肝炎患者医院感染特点及相关危险因素分析
- Author:
Xiaoyu LI
;
Yijun ZHU
;
Songping ZHANG
;
Chaodan LI
;
Mingli ZHU
- Publication Type:Journal Article
- Keywords:
Chronic severe hepatitis B;
Nosocomial infection;
Risk factors
- From:
Chinese Journal of Nosocomiology
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To analyze the characteristics of nosocomial infections,risk factors and prevention measures in patients with chronic severe hepatitis B.METHODS A retrospective review of the medical records of 354 patients with chronic severe hepatitis B admitted between Jan 2006 and Dec 2006 was performed.RESULTS The incidence of nosocomial infection in patients with chronic severe hepatitis B was 16.67% and mainly infection sites consisted of abdominal cavity(40.32%),and upper respiratory tract(22.58%).The most common infection(47.46%) was occurred during the period of hospitalization 15-30 days after and the most commonly pathogens were Gram-negative bacilli(68.75%).The infection risk factors were associated with invasive operation,hypoalbuminemia,endotoxemia,advanced age,antibiotics application and decrease in cell immune function.CONCLUSIONS It is important for the patients with chronic severe hepatitis B to strengthen management on related risk factors in order to prevent nosocomial infection effectively.
